Bookmakers made Jose Valenzuela a slight favorite against Edwin De Los Santos when they meet in their bout on Sunday 28th June 2026 at The Cosmopolitan of Las Vegas, Chelsea Ballroom, Las Vegas, United States.
He is currently 2/3 (-150) to win the bout outright, while you can get 1/1 (+100) on Edwin De Los Santos if you fancy the slight upset.
That means that oddsmakers think there is 55% chance of Valenzuela winning while giving Santos a 45% chance.
Valenzuela opened as the favorite at 4/6 (-150).
Santos opened at 11/10 (+110) which has got wider by -9/10 (+110).
The fight is scheduled for 10 rounds in the Lightweight division, which means both fighters will have to make the weight limit of 135 pounds (9.45 stones or 61.36 kg) on the day of the weigh-in.
Valenzuela vs Santos II Head To Head
Jose Valenzuela steps into the ring with a record of 15 wins, 3 losses, and 0 draws, 9 of those wins coming by way of knockout.
Edwin De Los Santos will make his way to the ring with a record of 17 wins, 2 losses and 0 draws, with 15 of those wins by knockout.
The stats suggest Santos has a large advantage in power over Valenzuela, boasting a 88% knockout percentage compared to Valenzuela's 60%.
Jose Valenzuela is the same age as Edwin De Los Santos, at 26 years old.
Jose Valenzuela fights out of the orthodox stance, while Edwin De Los Santos is a southpaw.
Valenzuela's experience as a professional fighter is relatively equal to Santos', having had 1 fewer fights, and made his debut in 2018, 28 days later than Santos, whose first professional fight was in 2018. He has fought 34 more professional rounds, totaling 95 compared to Santos' 61.
Jose Valenzuela goes into the fight ranked number 7 by the WBA at lightweight.
Valenzuela vs Santos II betting form
Valenzuela has beaten 3 of his last 5 opponents, stopping 1 of them, going the distance twice.
In his last fight, he won against Diego Torres on February 1, 2026, by unanimous decision in their 10 round contest at Meta Apex, Las Vegas, United States. He was a 2/15 (-770) favorite going into the ring.
Prior to that, he had been beaten by Gary Antuanne Russell on March 1, 2025, by unanimous decision in their WBA World Super Lightweight championship fight at Barclays Center, Brooklyn. He was a 21/20 (+100) underdog going into the ring.
Going into that contest, he had won against Isaac ‘Pitbull’ Cruz on August 3, 2024, by split decision in their WBA World Super Lightweight championship fight at BMO Stadium, Los Angeles. He was a 10/3 (+330) underdog going into the ring.
Before that, he had beaten Chris Colbert on December 16, 2023, by knockout in the 6th round at Armory, Minneapolis. He was a 4/5 (-130) favorite going into the ring.
He had lost to Chris Colbert on March 25, 2023, by unanimous decision in their 10 round contest at MGM Grand, Las Vegas. He was a 1/1 (+100) underdog going into the ring.
Santos has beaten 4 of his last 5 opponents, stopping 3 of them, going the distance once.
In his last fight, he defeated Eliot Chavez on December 13, 2025, by knockout in the 8th round in Dominican Republic.
Prior to that, he had been beaten by Shakur Stevenson on November 16, 2023, by unanimous decision in their WBC World Lightweight championship fight at T-Mobile Arena, Las Vegas, United States. He was a 13/2 (+650) underdog going into the contest.
Going into that contest, he had defeated Joseph Adorno on July 8, 2023, by unanimous decision in their 10 round contest at Boardwalk Hall, Atlantic City. He was a 3/10 (-330) favorite going into the contest.
Before that, he had won against Jose Valenzuela on September 4, 2022, by knockout in the 3rd round at Crypto.com Arena, Los Angeles.
He had defeated Luis Acosta on March 11, 2022, by knockout in the 2nd round at Deadwood Mountain Grand, Deadwood.
Who's been more active?
If you think ring rust and activity is a big factor in this fight, Jose Valenzuela has been fighting more than Edwin De Los Santos.
Jose Valenzuela last fought 4 months and 27 days ago, while Edwin De Los Santos' last outing was 6 months and 15 days ago.
Valenzuela's last 5 fights have come over a period of 3 years, 3 months and 3 days, which means he has been fighting approximately every 7 months and 26 days. In those fights, he fought a total of 50 rounds, meaning that they have lasted 10 rounds on average.
Santos' last 5 fights have come over a period of 4 years, 3 months and 17 days, meaning he has been fighting on average every 10 months and 10 days. In those fights, he fought a total of 35 rounds, meaning that they have lasted 7 rounds on average.
What’s the Latest Time I Can Bet on Valenzuela vs Santos Pre Fight?
The fighters are expected to ringwalk at around 11:00 PM EST / 8:00 PM PST at The Cosmopolitan of Las Vegas, Chelsea Ballroom, Las Vegas, United States, which is around 4:00 AM BST in the UK.
Where Can I Watch Valenzuela vs Santos for In-Play Betting?
Valenzuela vs Santos II will be broadcast on Paramount+ in the US, while the fight will be broadcast in the United Kingdom by Sky Sports Main Event.
